Arial view of the Integrated Science Building

Hanson Research

Development of Novel Methods

The Hanson group has an ongoing interest in the development of novel methods for the design and synthesis of diverse S- and P-heterocycles as potential small molecule drug probes/leads. Utilizing a diversity-oriented synthesis (DOS) approach in combination with a variety of metrics (bioinformatics), a number of protocols have been recently developed to access collections of diverse S-heterocycles, namely sultams.

In addition, current studies seek to probe the scope of phosphate-tether technology through its application to the total synthesis of several complexes, small molecule targets, and in the hopes of generating a suite of practical synthetic tools, studies will also include the development of a variety of new tether systems for potential use in the synthesis of biologically relevant molecules.