Publications

2020 – Present

  1. Dissanayake, G. C.; Ndi, C. N.; Markley, J. L.; Martinez, J. B.; Hanson, P. R. Total Synthesis of Sanctolide A and Formal Synthesis of (2S)‑Sanctolide A. J. Org. Chem. 2023, 88, 805–817.
    Accepted Dec. 1, 2022. Online Publication date January 5, 2023.
  2. Javed, S.; Ganguly, A.; Dissanayake, G. C.; Hanson, P. R. An iterative phosphate tether-mediated approach for the synthesis of complex polyols subunits. Org. Lett. 2022, 24, 16–21. 
  3. Ganguly, A.; Javed, S.; Bodugam, M.; Dissanayake, G.; Chegondi, R.; Hanson, P. R. Synthesis of the C1−C16 Polyol-Containing Macrolactone of 13-Desmethyl Lyngbouilloside, an Unnatural Analog of the Originally Assigned Structure of (−)-Lyngbouilloside. Israeli J. Chem. 2021, 61, 401–408.  Note-1: Israeli J. Chem. 2021, Volume 61, Issue 7–8. Special Issue Organometallic Door to Synthesis – Celebrating the 80th birthday of on Barry M. Trost.  Published Online April 14, 2021
    Equal contributions amongst authors.  Online Publication date Dec. 13, 2021.
  4. Jun, J. J. H., Duscharla, D., Ummanni, R., Hanson, P. R., Malhotra, S. Investigation on the anti-cancer activity of symmetric and unsymmetric cyclic sulfamides. ACS Med. Chem. Lett. 2021, 12, 202–210

2015 – 2019

  1. Faisal, S.; Zang, Q.; Brandhofer, A.; Maity, P. K.; Kearney, P.; Reiser, O.; Grass, R. N.; Stoianova, D. S.; Hanson. P. R. Development and Application of a Recyclable High Load Magnetic Co/C Hybrid ROMP-derived Benzene Sulfonyl Chloride Reagent and Utility of Corresponding Analogs. Org. Lett. 2017, 19, 2274– 2277. PMCID: PMC5595701
  2. Markley, J. L.; Hanson. P. R. P-Stereogenic Bicyclo[4.3.1]phosphite Boranes: Synthesis and Utility of Tunable P-Tether Systems for the Desymmetrization of C2-Symmetric 1,3-anti-Diols. Org. Lett., 2017, 19, 2552–2555.  PMCID: PMC5595702
  3. Markley, J. L.; Hanson. P. R.P-Tether-Mediated, Iterative SN2′-Cuprate Alkylation Strategy to Skipped Polyol Stereotetrads: Utility of an Oxidative “Function Switch” with Phosphite–Borane Tethers. Org. Lett., 2017, 19, 2556–2559.  PMCID: PMC5595703
  4. Javed, S.; Bodugam, M.; Torres, J.; Ganguly, A.; Hanson, P. R. Modular Synthesis of Novel Macrocycles Bearing α,β-Unsaturated Chemotypes through a Series of One-Pot, Sequential Protocols Chem. Eur. J. 2016, 22, 6755–6758. PMCID: PMC5094705​
  5. Bodugam, M.; Javed, S.; Ganguly, A.; Torres, J.; Hanson, P. R. A Pot-Economical Approach to the Total Synthesis of Sch-725674. Org. Lett. 2016, 18, 516–519. PMCID:​ PMC4852165
  6. Maitra, S.; Bodugam, M.; Javed, S.; Hanson, P. R. Synthesis of the C9-C25 Subunit of Spirastrellolide B. Org. Lett. 2016, 18, 3094–3097. PMCID:​ PMC494334
  7. Markley, J. L.; Maitra, S.; Hanson, P. R. Phosphate Tether-Mediated Ring-Closing Metathesis for the Generation of P-Stereogenic, Z-Configured Bicyclo[7.3.1]- and Bicyclo[8.3.1]phosphates. J. Org. Chem. 2016, 81, 899–911. PMCID:​ PMC4840021
  8. Faisal, S.; Maity, P. K.; Zang, Q.; Rolfe, A.; Hanson, P. R. Synthesis of High-Load, Hybrid Silica-Immobilized Heterocyclic Benzyl Phosphate (Si–OHBP) and Triazolyl Phosphate (Si–OHTP) Alkylating Reagents. ACS Comb. Sci. 2016, 18, 394–398. PMCID:​ PMC4943333
  9. Faisal, S.; Maity, P. K.; Zang, Q.; Samarakoon, T. B.; Sourk, R. L.; Hanson, P. R. Application of Silica Supported Alkylating Reagents in a One-Pot, Sequential Protocol to Diverse Benzoxathiazepine 1,1-Dioxides. ACS Comb. Sci. 2016, 18, 387–393. PMCID: PMC494330
  10. Maitra, S.; Markley, J. L.; Chegondi, R.; Hanson, P. R. Phosphate tether-mediated ring-closing metathesis for the generation of medium to large, P-stereogenic bicyclo[n.3.1]phosphates, Tetrahedron 2015, 71, 5734–5740.  Invited paper as part of the Tetrahedron Prize Award Symposium in Honor of Barry M. Trost and Jiro Tsuji. PMCID:​ PMC4584409​
  11. Jun, J. H.; Javed, S.; Ndi, C.; Hanson, P. R. Synthesis of P-, S-, Si-, B-, and Se-Heterocycles via Ring-Closing Metathesis. (Cossy et al, Eds), Part of the series Topics in Heterocyclic Chemistry, Springer, Berlin Heidelberg, 2015, 1–61. ISBN :978-3-319-39939-3​
  12. Maity, P. K.; Faisal, S.; Rolfe, A.; Stoianova, D.; Hanson, P. R. Silica-Supported Oligomeric Benzyl Phosphate (Si-OBP) and Triazole Phosphate (Si-OTP) Alkylating Reagents. J. Org. Chem. 2015, 80, 9942–9950. PMCID:​ PMC4848109
  13. Loh, J. K.; Asad, N.; Samarakoon, T. B.; Hanson, P. R. Modular, One-Pot, Sequential Aziridine Ring Opening–SNAr Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams. J. Org. Chem. 2015, 80, 9926–9941. PMCID:​ PMC4943336

2010 – 2014

  1. Hanson, P. R.; Jayasinghe, S.; Maitra, S.; Ndi, C. N.; Chegondi, R. A Modular Phosphate Tether-Mediated Divergent Strategy to Complex Polyols. Beilstein J. Org. Chem. 2014, 10, 2332–2337. Thematic Series of "Organophosphorus chemistry". PMCID: PMC4187035
  2. Asad, N.; Samarakoon, T. B.; Zang, Q.; Loh, J. K.; Javed, S.; Hanson, P. R. Rapid, Scalable Assembly of Stereochemically Rich, Mono- and Bicyclic Acyl Sultams. Org. Lett. 2014, 16, 82–85. PMCID: PMC4179432
  3. Jayasinghe, S.; Venukadasula, P. K. M.; Hanson, P. R. An Efficient, Modular Approach for the Synthesis of (+)-Strictifolione and a Related Natural Product. Org. Lett. 2014, 16, 122–125. PMCID: PMC4179430
  4. Basha, A.; Basha, F.; Ali, S. K.; Hanson, P. R.; Mitscher, L. A.; Oakley, B. R. Recent Progress in the Chemotherapy of Human Fungal Diseases. Emphasis on 1,3-β-Glucan Synthase and Chitin Synthase Inhibitors. Curr. Med. Chem. 2013, 20, 4859-4887.
  5. Chegondi, R.; Maitra, S.; Markley, J. L.; Hanson, P. R. Phosphate-Tether-mediated Ring-Closing Metathesis for the Preparation of Complex 1,3-anti-Diol-Containing Subunits. Chem. Eur. J. 2013, 19, 8088–8093. PMCID: PMC3823554
  6. Kainz, Q. M.; Linhardt, R.; Maity, P. K.; Hanson, P. R.; Reiser, O.  Ring-Opening Metathesis Polymerization-based Recyclable Magnetic Acylation Reagents. Chem. Sus. Chem. 2013, 6, 721–729.
  7. Faisal, S.; Ullah, F.; Maity, P. K.; Rolfe, A.; Samarakoon, T.; Porubsky, P.; Neunswander, B.; Lushington, G.; Basha, F.; Organ, M. G.; Hanson, P. R. Facile (Triazolyl)methylation of MACOS-derived Benzofused Sultams Utilizing ROMP-derived OTP Reagents.  ACS Comb. Sci. 2012, 14, 268–272. PMCID: PMC3656824
  8. Loh, J. K.; Yoon, S. Y.; Samarakoon, T. B.; Rolfe, A.; Porubsky, P.; Neuenswander, B.; Lushington, G. H.; Hanson, P. R. Exploring Diversity via a Modular Reaction Pairing Strategy. Beilstein J. Org. Chem. 2012, 8, 1293–1302. Thematic Series of "Recent developments in chemical diversity". PMCID: PMC3458752
  9. Ullah, F.; Zang, Q.; Javed, S.; Porubsky, P.; Neuenswander, B.; Lushington, G. H.; Bash, F. Z.; Hanson, P. R.; Organ, M. G.  Synthesis of Isoindoline Annulated Tricyclic Sultams Library via Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS).  Synthesis 2012, 44, 2547–2554.  Thematic issue on Flow Chemistry. PMCID: PMC3827362
  10. Ullah, F.; Zang, Q.; Javed, S.; Zhou, A.; Knudtson, C. A.; Bi, D.; Hanson, P. R.; Organ, M. G.  Multi Capillary Flow Reactor: Synthesis of 1,2,5-thiadiazepane 1,1-dioxide Library Utilizing One-Pot Elimination and Inter-/Intramolecular Double aza-Michael Addition Via Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS).  J. Flow Chem. 2012, 2, 118–123. PMCID: PMC3827364
  11. Venukadasula, P. K. M.; Chegondi, R.; Suryn, G.; Hanson, P. R. A Phosphate Tether-Mediated, One-Pot, Sequential Ring-Closing Metathesis/Cross-Metathesis/Chemoselective Hydrogenation Protocol. Org. Lett. 2012, 14, 2634–2637. PMCID: PMC3858481
  12. Zang, Q.; Javed, S.; Hill, D.; Ullah, F.; Bi, D.; Porubsky, P.; Neuenswander, B.; Lushington, G. H.; Santini, C.; Organ, M. G.; Hanson, P. R.  Automated Synthesis of a Library of Triazolated 1,2,5-Thiadiazepane 1,1-Dioxide via a Double aza-Michael Strategy. ACS Combi. Sci. 2012, 14, 456–459. PMCID: PMC3656823
  13. Zang, Q.; Javed, S.; Porubsky, P.; Ullah, F.; Neunswander, B.; Lushington, G.; Basha, F.; Organ, M. G.; Hanson, P. R. Synthesis of a Unique Isoindoline/Tetrahydroisoquinoline-based Tricyclic Sultam Library Utilizing a Heck-aza-Michael Strategy.  ACS Comb. Sci. 2012, 14, 211–217. PMCID: PMC341135
  14. Zang, Q.; Zhou, A.; Javed, S.; Maity, P. K.; Knudtson, C. A.; Bi, D.; Hastings, J. J.; Basha, F. Z.; Hanson, P. R.  Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-pot Sulfonylation/thia-Michael Protocol.  Heterocycles 2012, 86, 1661–1674. PMCID: PMC3873773
  15. Zang, Q.; Javed, S.; Zhou, A.; Knudtson, C. A.; Bi, D.; Basha, F. Z.; Hanson, P. R.  Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 2: Routes to Bicyclic Sultams.  Heterocycles 2012, 86, 1675–1688. PMCID: PMC3873775
  16. Asad, N.; Hanson, P. R.; Long, T. R.; Rayabarapu, D. K.; Rolfe, A. Synthesis of epoxybenzo[d]isothiazole 1,1-dioxides: ROMP purification via sequestration of excess oxa-norbornene sultams. Chem. Commun. 2011, 47, 9528–9530. PMCID: PMC3271945
  17. Chegondi, R.; Tan, M. M. L.; Hanson, P. R. Phosphate Tether-Mediated Approach to the Formal Synthesis of (–)-Salicylihalamides A and B. J. Org. Chem. 2011, 76, 3909–3916. PMCID: PMC3271935
  18. Fenster, E.; Long, T.; Zang, Q.; Hill, D.; Neunswander, B.; Lushington, G.; Zhao, A.-H.; Santini, C.; Hanson, P. R. Automated Synthesis of a 184-Member Library of Thiadiazepan-1,1-dioxide-4-ones. ACS Comb. Sci. 2011, 13, 244–250. PMCID: PMC3090501
  19. Hanson, P. R.; Chegondi, R.; Nguyen, J.; Thomas, C. D.; Waetzig, J.; Whitehead, A. Total Synthesis of Dolabelide C: A Phosphate-Mediated Approach. J. Org. Chem. 2011, 76, 4358–4370. Feature Article. PMCID: PMC3150593
  20. Long, T. R.; Faisal, S.; Maity, P. K.; Rolfe, A.; Kurtz, R.; Klimberg, S. K.; Najjar, R.; Basha, F.; Hanson, P. R. “Click”-Capture, Ring-Opening Metathesis Polymerization (ROMP), Release: Facile Triazolation Utilizing ROMP-Derived Oligomeric Phosphates. Org. Lett. 2011, 13, 2038–2041. PMCID: PMC3098766
  21. Maity, P. K.; Kainz, Q. M.; Faisal, S.; Rolfe, A.; Samarakoon, T. B.; Basha, F. Z.; Reiser, O.; Hanson, P. R. Intramolecular Monomer-on-Monomer (MoM) Mitsunobu Cyclization for the Synthesis of Thiadiazepine-dioxides. Chem. Commun. 2011, 47, 12524–12526. PMCID: PMC3271939
  22. Maity, P. K.; Rolfe, A.; Samarakoon, T. B.; Faisal, S.; Kurtz, R. D.; Long, T. R.; Schatz, A.; Flynn, D. L.; Grass, R. N.; Stark, W. J.; Reiser, O.; Hanson, P. R. Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration. Org. Lett. 2011, 13, 8–10. PMCID: PMC3271942
  23. Organ, M. G.; Hanson, P. R.; Rolfe, A.; Samarakoon, T. B.; Ullah, F. Accessing Stereochemically Rich Sultams via Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS) Scale-out. J. Flow Chem. 2011, 1, 32–39. Thematic issue on Flow. PMCID: PMC3221740
  24. Rolfe, A.; Loh, J. K.; Maity, P. K.; Hanson, P. R. High-Load, Hybrid Si-ROMP Reagents. Org. Lett. 2011, 13, 4–7. PMCID: PMC3271940
  25. Rolfe, A.; Painter, T. O.; Asad, N.; Hur, M. Y.; Jeon, K. O.; Brzozowski, M.; Klimberg, S. V.; Porubsky, P.; Neunswander, B.; Lushington, G.; Santini, C.; Hanson, P. R. Triazole-Containing Isothiazolidine 1,1-Dioxide Library Synthesis: One-Pot, Multi-Component Protocols for Small Molecular Probe Discovery. ACS Comb. Sci. 2011, 13, 511–517. PMCID: PMC3271941
  26. Rolfe, A.; Ullah, F.; Samarakoon, T. B.; Kurtz, R. D.; Porubsky, P.; Neunswander, B.; Lushington, G.; Santini, C.; Organ. M. G.; Hanson, P. R. Synthesis of Amino-Benzothiaoxazepine-1,1-dioxides Utilizing a Microwave-Assisted, SNAr Protocol. ACS Comb. Sci. 2011, 13, 653–658. PMCID: PMC3271943
  27. Samarakoon, T. B.; Loh, J. K.; Rolfe, A.; Le, L. S.; Yoon, S. Y.; Lushington, G. H.; Hanson, P. R. A Molecular Reaction Pairing Approach to the Diversity-Oriented Synthesis of Fused- and Bridged-Polycyclic Sultams. Org. Lett. 2011, 13, 5148–5151. PMCID: PMC3271938
  28. Zang, Q.; Javed, S.; Ullah, F.; Zhou, A.; Knudtson, C. A.; Bi, D.; Bashac, F. Z.; Organ, M. G.; Hanson, P. R. Application of a Double aza-Michael Reaction in a "Click, Click, Cy-Click" Strategy: From Bench to Flow. Synthesis 2011, 2743–2750. Thematic Issue on Click Chemistry. PMCID: PMC3171749
  29. Long, T.; Maity, P. K.; Samarakoon T. B.; Hanson P. R. ROMP-Derived Oligomeric Phosphates for Application in Facile Benzylation. Org. Lett. 2010, 12, 2904–2907. PMCID: PMC2925234
  30. Rolfe, A.; Lushington, G. H.; Hanson, P. R. Reagent Based DOS: A Click, Click, Cyclize Strategy to Probe Chemical Space. Org. Biomol. Chem. 2010, 8, 2198–2203. PMCID: PMC2888000
  31. Rolfe, A.; Samarakoon, T. B.; Hanson, P. R. Formal [4+3] Epoxide Cascade Reaction via a Complementary Ambiphilic Pairing Strategy. Org. Lett. 2010, 12, 1216–1219. PMCID: PMC2864497
  32. Rolfe, A.; Samarakoon, T. B.; Klimberg, S. V.; Brzozowski, M.; Neuenswander, B.; Lushington, G. H.; Hanson, P. R. SNAr-Based, Facile Synthesis of a Library of Benzothiaoxazepine-1,1′-dioxides. J. Comb. Chem. 2010, 12, 850–854. PMCID: PMC3098767
  33. Samarakoon, T. B.; Hur, M. Y.; Kurtz, R. D.; Hanson, P. R. A Formal [4+4] Complementary Ambiphile Pairing (CAP) Reaction: A New Cyclization Pathway for ortho-Quinone Methides. Org. Lett. 2010, 12, 2182–2185. PMCID: PMC2888001
  34. Schätz, A.; Long, T. R.; Grass, R. N.; Stark, W. J.; Hanson, P. R.; Reiser, O. Immobilization on a Nanomagnetic Co/C Surface using ROM Polymerization: Generation of a Novel Hybrid Material as Support for a Recyclable Palladium Catalyst. Adv. Func. Mat. 2010, 20, 4323–4328. PMCID: PMC3271946
  35. Thomas, C. D.; Hanson, P. R. Phosphorus and Sulfur Heterocycles via Ring-Closing Metathesis: Application in Natural Product Synthesis. Metathesis in Natural Product Synthesis. (J. Cossy, S. Areniyadis, C. Meyer, Eds ), Wiley-VCH: Weinheim, Germany, 2010, pp. 129–144.
  36. Ullah, F.; Samarakoon, T. B.; Rolfe, A.; Kurtz, R. D.; Hanson, P. R.; Organ, M. G. Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofusedsultams Benzthiaoxazepine-1,1-dioxides. Chem. Eur. J. 2010, 10959–10962. PMCID: PMC3145490
  37. Venukadasula, P. K. M.; Chegondi, R.; Maitra, S.; Hanson, P. R. A Concise, Phosphate-Mediated Approach to the Total Synthesis of (–)-Tetrahydrolipstatin. Org. Lett. 2010, 12, 1556–1559. PMCID: PMC2888003

2005 – 2009

  1. Jeon, K. O.; Rayabarapu, D.; Rolfe, A.; Volp, K.; Omar, I.; Hanson, P. R. Metathesis Cascade Strategies (ROM-RCM-CM): A DOS Approach to Skeletally Diverse Sultams. Tetrahedron 2009, 65, 4992–5000. PMCID: PMC2702866
  2. Rayabarapu, D.; Zhou, A.; Jeon, K. O.; Samarakoon, T.; Rolfe, A.; Siddiqui, H.; Hanson, P. R. α-Haloarylsulfonamides: Multiple Cyclization Pathways to Skeletally Diverse Benzofused Sultams. Tetrahedron 2009, 65, 3180–3188. PMCID: PMC2702864
  3. Rolfe, A.; Hanson, P. R. Microwave-assisted Sequential One-pot Protocol to Benzothiadiazin-3-one-1,1-dioxides via a Copper-catalyzed N-Arylation Strategy. Tetrahedron Lett. 2009, 50, 6935–6937. PMCID: PMC2888103
  4. Rolfe, A.; Young, K.; Volp, K.; Schoenen, F.; Neuenswander, B.; Lushington, G. H.; Hanson, P. R.
    A One-Pot, 3-Component, Domino Heck-aza-Michael Approach to Libraries of Functionalized 1,1-Dioxido-1,2-benzisothiazoline-3-acetic acids. J. Comb. Chem. 2009, 11, 732–738. PMCID: PMC2895961
  5. Thomas, C. D.; McParland, J. P.; Hanson, P. R. Divalent and Multivalent Activation in Phosphate Triesters: A Versatile Method for the Synthesis of Advanced Polyol Synthons. Eur. J. Org. Chem. 2009, 5487–5500. PMCID: PMC3526009
  6. Zhou, A.; Rayabarapu, D.; Hanson, P. R. "Click, Click, Cyclize”: A DOS Approach to Sultams Utilizing Vinyl Sulfonamide Linchpins. Org. Lett. 2009, 11, 531–534. PMCID: PMC2742886
  7. Fenster, E.; Rayabarapu, D. K.; Zhang, M.; Mukherjee, S.; Hill, D.; Neuenswander, B.; Schoenen, F.; Hanson, P. R.; Aubé, J. Three-Component Synthesis of 1,4-Diazepin-5-ones and the Construction of γ -Turn-like Peptidomimetic Libraries. J. Comb. Chem. 2008,10, 230–234.
  8. Hanson, P. R.; Samarakoon, T.; Rolfe, A. Supported/Tagged Scavengers for Facilitating High-throughput Chemistry. In The Power of Functional Resins in Organic Synthesis. (F. Albericio, J. Tulla-Puche, Eds), Wiley-VCH: Weinheim, Germany, 2008, pp 183–223.
  9. Jiménez-Hopkins, M.; Hanson, P. R. An RCM Strategy to Stereodiverse δ-Sultam Scaffolds. Org. Lett. 2008, 10, 2223–2226. PMCID: PMC2641035
  10. Rolfe, A.; Probst, D.; Volp, K.; Omar, I.; Flynn, D.; Hanson, P. R. High-load, Oligomeric dichlorotriazine (ODCT): A Versatile ROMP-derived Reagent and Scavenger. J. Org. Chem. 2008, 73, 8785–8790. PMCID: PMC3271944
  11. Rolfe, A.; Young, K.; Hanson, P. R. Domino Heck-Aza-Michael Reactions: A One-pot, Multi-Component Approach to 1,2-Benzisothiazoline-3-acetic acid 1,1-dioxides. Eur. J. Org. Chem. 2008, 5254–5262. PMCID: PMC2709420
  12. Stoianova, D. S.; Yao, L.; Rolfe, A.; Samarakoon, T.; Hanson, P. R. High-load, Oligomeric Monoamine Hydrochloride: Facile Generation via ROM Polymerization and Application as an Electrophile Scavenger. Tetrahedron Lett. 2008,49, 4553–4555. PMCID: PMC2659622
  13. Vedantham, P.; Zhang, M.; Gor, P. J.; Huang, M.; Georg, G. I.; Lushington, G. H.; Mitscher, L. A.; Ye, Q.-Z.; Hanson, P. R. Studies Towards the Synthesis of Methionine Aminopeptidase Inhibitors: Diversification Utilizing a ROMP-Derived Coupling Reagent. J. Comb. Chem.2008,10, 195–203.
  14. Vedantham, P.; Guerra, J. M.; Schoenen, F.; Huang, M.; Gor, P. J.; Georg, G. I.; Wang, J. L.; Neuenswander, B.; Lushington, G.H.; Mitscher, L. A.; Ye, Q.-Z.; Hanson, P. R. Ionic Immobilization, Diversification, and Release: Application to the Generation of a Library of Methionine Aminopeptidase Inhibitors. J. Comb. Chem. 2008,10, 185–194.
  15. Waetzig, J. D.; Hanson, P. R. A Multifaceted Phosphate Tether: Application to the C1-C14 Subunit of Dolabelides A-D. Org. Lett. 2008, 10, 109–112. PMCID: PMC2640944
  16. Whitehead, A.; Waetzig, J. D.; Thomas, C. D.; Hanson, P. R. A Multifaceted Phosphate Tether: Application to the C15-C30 Subunit of Dolabelides A-D. Org. Lett. 2008,10, 1421–1424. PMCID: PMC2641022
  17. Zhou, A.; Hanson, P. R. Synthesis of Sultam Scaffolds via Intramolecular Oxa-Michael and Diastereoselective Baylis−Hillman Reactions. Org. Lett. 2008, 10, 2951–2954. PMCID: PMC2742884
  18. Dirscherl, G.; Knape, R.; Hanson, P.; Koenig, B. Solid-phase Synthesis of Metal-Complex Containing Peptides. Tetrahedron 2007, 63, 4918–4928.
  19. Zhang, M.; Flynn, D. L.; Hanson, P. R. Oligomeric Benzylsulfonium Salts: Facile Benzylation via High-Load ROMP Reagents. J. Org. Chem. 2007, 72, 3194–3198.
  20. Ahn, Y. M.; Vogeti, L.; Liu, C-J.; Santhapuram, H. K. R.; White, J. M.; Vasandani, V.; Mitscher, L. A.; Lushington, G. H.; Hanson, P. R.; Powell, D. R.; Himes, R. H.; Roby, K. F.; Ye, Q.; Georg, G. I. Design, Synthesis, and Antiproliferative and CDK2-cyclin a Inhibitory Activity of Novel Flavopiridol Analogues. Bioorg. & Med. Chem. 2007, 15, 702–713. PMCID: PMC187666
  21. Sieck, S. R.; McReynolds, M. D.; Schroeder, C. E.; Hanson, P. R. Metathesis Studies to Cyclic Enol Phosphonamidates. J. Organomet. Chem. 2006, 691, 5307–5311.
  22. Whitehead, A.; McParland, J. P.; Hanson, P. R. Divalent Activation in Temporary Phosphate Tethers: Highly Selective Cuprate Displacement Reactions. Org. Lett. 2006, 8, 5025–5028.
  23. Herpel, R. H.; Vedantham, P.; Flynn, D. L.; Hanson, P. R. High-load, Oligomeric Phosphonyl Dichloride: Facile Generation via ROM Polymerization and Applications to Scavenging Amines. Tetrahedron Lett. 2006,47, 6429–6432.
  24. Waetzig, J. D.; Hanson, P. R. Temporary Phosphate Tethers: A Metathesis Strategy to Differentiated Polyol Subunits. Org. Lett. 2006, 8, 1673–1676.
  25. Harned, A. M.; Sherrill, W. M.; Flynn, D. L.; Hanson, P. R. High-Load, Soluble Oligomeric Benzenesulfonyl Azide: Applications to Facile Diazo-Transfer Reactions. Tetrahedron 2005, 61, 12093–12099.
  26. Whitehead, A.; McReynolds, M. D.; Moore, J. D.; Hanson, P. R. Multivalent Activation in Phosphate Tethers: A New Tether for Small Molecule Synthesis. Org. Lett. 2005, 7, 3375–3378.
  27. Stoianova, D. S.; Whitehead, A.; Hanson, P. R. P-Heterocyclic Building Blocks: Application to the Stereoselective Synthesis of P-Sugars. J. Org. Chem. 2005,70, 5880–5889.
  28. Dougherty, J. M.; Jimenez, M.; Hanson, P. R. Synthesis of Cyclic Sulfamoyl Carbamates and Ureas via Ring-Closing Metathesis. Tetrahedron 2005, 61, 6218–6230.
  29. Harned, A. M.; Song He, H.; Toy, P. H.; Flynn, D. L.; Hanson, P. R. Multipolymer Solution-Phase Reactions: Application to the Mitsunobu Reaction. J. Am. Chem. Soc. 2005, 127, 52–53.
  30. Harned, A. M.; Zhang, M.; Vedantham, P.; Mukherjee, S.; Herpel, R. H.; Flynn, D. L.; Hanson, P. R. ROM Polymerization in Facilitated Synthesis. Aldrichimica Acta, 2005, 38(1), 3.

2000 – 2004

  1. Zhang, M.; Vedantham, P.; Flynn, D. L.; Hanson, P. R. High-Load, Soluble Oligomeric Carbodiimide: Synthesis and Application in Coupling Reactions. J. Org. Chem. 2004, 69, 8340-8344.
  2. Zhang, M., Moore, J.D., Flynn, D.L., Hanson, P.R. Development of High-Load, Soluble, Oligomeric Sulfonate Esters via ROM Polymerization: Applications to the Benzylation of Amines. Org. Lett., 2004, 6, 2657-2660.
  3. McReynolds, M. D.; Dougherty, J. M.; Hanson, P. R. Synthesis of Phosphorus and Sulfur Heterocycles via Ring-Closing Olefin Metathesis. Chem. Rev. 2004, 104, 2239-2258.
  4. Jun, J. H.; Dougherty, J. M.; Jimenez, M. S.; Hanson, P. R. New Strategies to Symmetric and Unsymmetric Cyclic Sulfamide Analogs of DMP 323: A "Sulfur Linchpin"/RCM Approach. Tetrahedron 2003, 59, 8901-8912.
  5. Mukherjee, S.; Poon, K. W. C.; Flynn, D. L.; Hanson, P. R. Capture-ROMP-Release: Application to the Synthesis of Amines and Alkylhydrazines. Tetrahedron Lett. 2003, 44, 7187-7190.
  6. Moore, J. D.; Byrne, R. J.; Vedantham, P.; Flynn, D. L.; Hanson, P. R. High-Load, ROMP-Generated Oligomeric Bis-acid Chlorides: Design of Soluble and Insoluble Nucleophile Scavengers. Org. Lett. 2003, 5, 4241-4244.
  7. Harned, A. M.; Probst, D. A.; Hanson, P. R. The Use of Olefin Metathesis in Combinatorial Chemistry: Supported and Chromatography-Free Syntheses. in Handbook of Metathesis. Grubbs, R. H., Ed.: Wiley-VCH: Weinheim, 2003. pp 361-402.
  8. Whitehead, A.; Moore, J. D.; Hanson, P. R. A convenient approach to cyclic enol phosphates via ring-closing metathesis. Tetrahedron Lett. 2003, 44, 4275-4277.
  9. Moore, J. D.; Hanson, P. R. Substituent Effects in the Double Diastereotopic Differentiation of α-Diazophosphonates via Intramolecular Cyclopropanation. Tetrahedron: Asymmetry 2003, 14, 873-880.
  10. Moore, J. D.; Herpel, R. H.; Lichtsinn, J. R.; Flynn, D. L.; Hanson, P. R. ROMP-Generated Oligomeric Sulfonyl Chlorides as Versatile Soluble Scavenging Agents. Org. Lett. 2003, 5, 105-107.
  11. Harned, A. M.; Mukherjee, S.; Flynn, D. L.; Hanson, P. R. Ring-Opening Metathesis Phase-Trafficking (ROMpt) Synthesis: Multistep Synthesis on Soluble ROM Supports. Org. Lett. 2003, 5, 15-18.
  12. Flynn D. L.; Hanson P. R.; Berk S. C.; Makara G. M. New Developments in Chemical Library Synthesis. Norbornenyl Tags for Use in Phase-Switching, Sequestration, Capture-Release and Soluble Support Applications. Curr Opin Drug Discov Devel 2002, 5, 571-579.
  13. McReynolds, M. D.; Sprott, K. T.; Hanson, P. R. A Concise Route to Structurally Diverse DMP 323 Analogues via Highly Functionalized 1,4-Diamines. Org. Lett. 2002, 4, 4673-4676.
  14. Moore, J. D.; Sprott, K. T.; Hanson, P. R. Conformationally Constrained α-Boc-Aminophosphonates via Transition Metal-Catalyzed/Curtius Rearrangement Strategies. J. Org. Chem. 2002, 67, 8123-8129.
  15. Moore, J. D.; Sprott, K. T.; Wrobleski, A. D.; Hanson, P. R. Double Diastereoselective Intramolecular Cyclopropanation to P-Chiral [3.1.0]-Bicyclic Phosphonates. Org. Lett. 2002, 4, 2357-2360.
  16. Moore, J. D.; Harned, A. M.; Henle, J.; Flynn, D. L.; Hanson, P. R. Scavenge-ROMP-Filter: A Facile Strategy for Soluble Scavenging via Norbornenyl Tagging of Electrophilic Reagents. Org. Lett. 2002, 4, 1847-1849.
  17. Harned, A. M.; Hanson, P. R. Capture-ROMP-Release: Application for the Synthesis of O-Alkyl Hydroxylamines. Org. Lett. 2002, 4, 1007-1010.
  18. Wanner, J.; Harned, A. M.; Probst, D. A.; Poon, K. W. C.; Klein, T. A.; Snelgrove, K. A.; Hanson, P. R. A Dual Metathesis Route to Oligomeric Sulfonamides. Tetrahedron Lett. 2002, 43, 917-921.
  19. Sprott, K. T.; McReynolds, M. D.; Hanson, P. R. A Temporary Phosphorus Tether/Ring-Closing Metathesis Strategy to Functionalized 1,4-Diamines. Org. Lett. 2001, 3, 3939-3942.
  20. Stoianova, D. S.; Hanson, P. R. A Ring-Closing Metathesis Strategy to Phosphonosugars. Org. Lett. 2001, 3, 3285-3288.
  21. Sprott, K. T.; McReynolds, M. D.; Hanson, P. R. Ring-closing metathesis strategies to amino acid-derived P-heterocycles. Synthesis 2001, 612-620.
  22. Moore, J. D.; Sprott, K. T.; Hanson, P. R. New strategies to cyclic α-thiophosphonates. Synlett 2001, 605-608.
  23. Dougherty, J. M.; Probst, D. A.; Robinson, R. E.; Moore, J. D.; Klein, T. A.; Snelgrove, K. A.; Hanson, P. R. Ring-Closing Metathesis Strategies to Cyclic Sulfamide Peptidomimetics. Tetrahedron 2000, 56, 9781-9790.
  24. Sprott, K. T.; Hanson, P. R. The Synthesis of Sterically Demanding Amino Acid-Derived Cyclic Phosphonamides. J. Org. Chem. 2000, 65, 7913-7918.
  25. Sprott, K. T.; Hanson, P. R. The Synthesis of P-Chiral Amino Acid-Derived Phosphonamidic Anhydrides. J. Org. Chem. 2000, 65, 4721-4728.
  26. Stoianova, D. S.; Hanson, P. R. Diastereotopic Differentiation on Phosphorus Templates via the Ring-Closing Metathesis Reaction. Org. Lett. 2000, 2, 1769-1772.

1996 - 1999

  1. Hanson, P. R.; Probst, D. A.; Robinson, R. E.; Yau, M. Cyclic sulfonamides via the ring-closing metathesis reaction. Tetrahedron Lett. 1999, 40, 4761–4764.
  2. Hanson, P. R.; Stoianova, D. S. Ring-closing metathesis strategy to P-heterocycles. Tetrahedron Lett. 1999, 40, 3297–3300.
  3. Hanson, P. R.; Sprott, K. T.; Wrobleski, A. D. Intramolecular cyclopropanation reactions en route to novel P-heterocycles. Tetrahedron Lett. 1999, 40, 1455–1458.
  4. Hanson, P. R.; Stoianova, D. S. Ring closing metathesis reactions on a phosphonate template. Tetrahedron Lett. 1998, 39, 3939–3942.